If you have diabetes or prediabetes, your HbA1c is probably the number your GP talks about most. But what does it actually measure, how reliable is it, and what should you do with the result? Here is a clear, plain-English guide.

What HbA1c Measures

HbA1c — haemoglobin A1c, also called glycated haemoglobin — measures the percentage of haemoglobin (the protein in red blood cells) that has glucose attached to it. Because red blood cells live for roughly 10–12 weeks, HbA1c reflects your average blood sugar over approximately the past three months. Unlike a finger-prick test that shows a single moment in time, HbA1c gives a longer-term picture of control.

What the Numbers Mean

Reducing HbA1c matters: Every 1% (11 mmol/mol) reduction in HbA1c is associated with a 21% reduction in diabetes-related deaths, a 37% reduction in microvascular complications (eye and kidney damage), and a 14% reduction in heart attacks, according to the landmark UKPDS study.

Limitations to Be Aware Of

HbA1c is not perfect. It can give misleading results in people with certain anaemias, haemoglobin variants (more common in some ethnic groups), or kidney disease. Pregnancy also affects the reading. If your GP suspects these factors may apply, they may use alternative tests such as fructosamine or continuous glucose monitoring.

How Often Should You Be Tested?